Vitamin B12 Research Today is a free monthly online journal that collates and summarizes the latest research about Vitamin B12, including details on cyanocobalamin, benefits, supplements, deficiency, side-effects, sources.

Natural-abundance 15N--13C correlation spectra of vitamin B-12.

Kupce E, Freeman R

Varian, Ltd, 6 Mead Road, Yarnton, Oxford, UK.

Two-dimensional nitrogen-carbon NMR correlation spectra have been derived by a new reconstruction technique based on standard two-dimensional HMQC and HMBC spectra, and operating with natural 15N and 13C isotopic abundances. Compared with conventional three-dimensional spectroscopy in which 15N and 13C spins must be present in the same molecule, the reconstruction method offers two orders of magnitude improvement in sensitivity. Vitamin B-12 serves as an illustrative example.

Published 9 January 2007 in Magn Reson Chem, 45(2): 103-5.
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